This website is dedicated to increasing awareness of a variety of health conditions in particular Pyroluria, also known as Pyrrole Disorder, Kryptopyrroles, hemepyrrolin or Mauve Factor. Conquering Pyroluria was originally created as a place where people could find information on Pyroluria but has since grown to encompass many more health conditions including; Candida, Leaky Gut Syndrome, low GABA levels, along with mental health disorders including, Depression and Anxiety.
Unfortunately, Pyroluria is not yet readily accepted by mainstream medicine and as such, sufferers often get misdiagnosed and treated unnecessarily with pharmaceutical drugs, which can have unfortunate side effects. As a health condition, it has been documented for many decades with the initial work beginning in 1958 with Dr Abraham Hoffer. It was further researched in the 1970s by Dr Carl Pfeiffer and his team who introduced Pyroluria testing and treatment protocols.
Pyroluria was initially believed to be a genetic abnormality, but further research and ongoing clinical treatment has discovered various lifestyle factors, such as Leaky Gut Syndrome, stress, intestinal dysbiosis, poor diet and inadequate digestive function can also exacerbate or cause many of the symptoms surrounding Pyroluria.
What occurs in a Pyroluria sufferer is that they produce excessive amounts of a chemical substance called Hydroxyl-hemopyrolin 2-one commonly known as HPL. HPL binds to, inhibits and causes the excretion of various nutrients including zinc, vitamin B6 and biotin resulting in their deficiencies. This can lead to any number of health complaints especially mental health disorders such as attention deficit hyperactivity disorder (ADHD), schizophrenia, depression and anxiety.
Nutritional deficiencies play havoc with our health and emotional wellbeing, for example; zinc deficiency can lead to common immunological disorders and it often presents as white spots on nails, stretch marks, food allergies or acne. Whereas a vitamin B6 deficiency can lead to many chronic mental health disorders including depression and anxiety. Vitamin B6 deficiency is often associated with seborrhoeic dermatitis, neuropathy or a sore and inflamed tongue. Biotin deficiency is similar to vitamin B6 deficiency in that it can lead to mental health disorders, but is commonly related to skin rashes especially around the mouth, fine brittle hair, candida and baldness.
For a Pyroluria sufferer, zinc deficiency and vitamin b6 deficiency will lead to a reduction in neurotransmitter (brain chemical) levels, resulting in Low GABA levels, serotonin and dopamine deficiencies. These deficiencies can affect us emotionally and lead to a worsening of symptoms and mental health disorders including mood swings, depression and anxiety.
Hopefully, the information presented throughout the Conquering Pyroluria website will broaden your understanding not only of Pyroluria but physical ailments and mental health disorders. Please click on the free sources tab or FREE RESOURCES link where you’ll find information on foods, blog articles, health conditions including signs and symptoms, as well as audio and video downloads.
For those interested in finding out if they suffer from this condition we offer Pyroluria Testing. If you have already tested positive or borderline we have a lot of information on treatment, which is found in the Pyroluria Treatment tab.
We wish you well on your journey of understanding, healing and living a great life!